Single-Cell Transcriptomics Analyses of Neural Stem Cell Heterogeneity and Contextual Plasticity in a Zebrafish Brain Model of Amyloid Toxicity
时间：2019-04-23
期刊：Cell Rep.
Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion
时间：2019-04-18
期刊：Biorxiv.
Natural Genetic Variation Reveals Key Features of Epigenetic and Transcriptional Memory in Virus-Specific CD8 T Cells
时间：2019-04-16
期刊：Immunity.
Characterization of pediatric hepatocellular carcinoma reveals genomic heterogeneity and diverse signaling pathway activation
时间：2019-04-11
期刊：Pediatr Blood Cancer.
Spatiotemporal Dynamics of Molecular Pathology in Amyotrophic Lateral Sclerosis
时间：2019-04-05
期刊：Science
Adventitial Cell Atlas of wt (Wild Type) and ApoE (Apolipoprotein E)-Deficient Mice Defined by Single-Cell RNA Sequencing
时间：2019-04-04
期刊：Arterioscler Thromb Vasc Biol.
Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion
时间：2019-04-01
期刊：Nat Immunol.
A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma
时间：2019-03-29
期刊：cell
Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions
时间：2019-03-28
期刊：cell
Crossreactive public TCR sequences undergo positive selection in the human thymic repertoire
时间：2019-03-28
期刊：J Clin Invest.
Molecular Support for Heterogonesis Resulting in Sesquizygotic Twinning
时间：2019-03-28
期刊：N Engl J Med
Single cell RNA sequencing identifies TGFβ as a key regenerative cue following LPS-induced lung injury
时间：2019-03-26
期刊：JCI Insight.
Single-Cell Transcriptome Analysis of CD34+ Stem Cell-Derived Myeloid Cells Infected With Human Cytomegalovirus
时间：2019-03-21
期刊：Front Microbiol
Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response
时间：2019-03-21
期刊：Cell Stem Cell
Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans
时间：2019-03-19
期刊：Nat Commun.
Molecular profiling of resident and infiltrating mononuclear phagocytes during rapid adult retinal degeneration using single-cell RNA sequencing
时间：2019-03-19
期刊：Sci Rep.
Epigenetic Regulation of IL-17-Induced Chemokines in Lung Epithelial Cells
时间：2019-03-17
期刊：Mediators Inflamm.
Identification of a neoantigen epitope in a melanoma patient with good response to anti-PD-1 antibody therapy
时间：2019-03-14
期刊：Immunity Lett.
Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis
时间：2019-03-12
期刊：Nat Commun.
Altered neuronal migratory trajectories in human cerebral organoids derived from individuals with neuronal heterotopia
时间：2019-03-11
期刊：Nat Med.
Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β-induced Serpine1
时间：2019-03-11
期刊：J Clin Invest.
Colonic epithelial cell diversity in health and inflammatory bowel disease
时间：2019-02-27
期刊：Nature
Role of alternative polyadenylation dynamics in acute myeloid leukaemia at single-cell resolution
时间：2019-02-27
期刊：RNA Biol.
Single-cell analysis of fate-mapped macrophages reveals heterogeneity, including stem-like properties, during atherosclerosis progression and regression
时间：2019-02-21
期刊：JCI Insight
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
时间：2019-02-18
期刊：Nat Immunol.
Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function
时间：2019-02-15
期刊：Nat Commun.
Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer
时间：2019-02-15
期刊：Nat Immunol.
Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes
时间：2019-02-14
期刊：Cell Metab.
Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells
时间：2019-02-13
期刊：Nature
Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo
时间：2019-02-11
期刊：Cell Syst.
Proliferation tracing with single-cell mass cytometry optimizes generation of stem cell memory-like T cells
时间：2019-02-11
期刊：Nat Biotechnol
Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells
时间：2019-02-08
期刊：J Exp Med
Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice
时间：2019-02-07
期刊：JCI Insight
Single-cell profiling of cutaneous T-cell lymphoma reveals underlying heterogeneity associated with disease progression
时间：2019-02-04
期刊：Clin Cancer Res.
Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium
时间：2019-01-25
期刊：Cell
Inflammation-induced glycolytic switch controls suppressivity of mesenchymal stem cells via STAT1 glycosylation
时间：2019-01-24
期刊：Leukemia.
Altered human oligodendrocyte heterogeneity in multiple sclerosis
时间：2019-01-23
期刊：Nature
Memory CD4+ T cells are generated in the human fetal intestine
时间：2019-01-21
期刊：Nat Immunol.
Thymic regulatory T cells arise via two distinct developmental programs
时间：2019-01-14
期刊：Nat Immunol.
The Emergence and Functional Fitness of Memory CD4+ T Cells Require the Transcription Factor Thpok
时间：2019-01-08
期刊：Immunity.
Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction
时间：2019-01
期刊：Nat Immunol.
Immunomodulatory activity of lenvatinib contributes to antitumor activity in the Hepa1-6 hepatocellular carcinoma model
时间：2018-12
期刊：Cancer Sci.
Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma
时间：2018-12
期刊：Nat Med
Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1-CD8+ Tumor-Infiltrating T Cells
时间：2018-12-28
期刊：Immunity.
Single-cell RNA-Seq of lymphoma cancers reveals malignant B cell types and co-expression of T cell immune checkpoints
时间：2018-12-27
期刊：Blood
Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity
时间：2018-12-19
期刊：Nature
Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss
时间：2018-12-17
期刊：Nat Med.
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
时间：2018-12-17
期刊：Nature.
Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis
时间：2018-12-15
期刊：Am J Respir Crit Care Med.
NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology
时间：2018-12-14
期刊：Ann Rheum Dis.
Organoid Modeling of the Tumor Immune Microenvironment
时间：2018-12-13
期刊：Cell
Genome-wide CRISPR Screens in Pri-3-y Human T Cells Reveal Key Regulators of Immune Function
时间：2018-12-13
期刊：Cell
Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors
时间：2018-12-11
期刊：Stem Cell Reports.
Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury
时间：2018-12-06
期刊：Science.
Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Pri-3-y Hepatocytes in 3D Culture
时间：2018-11-29
期刊：cell
Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12
时间：2018-11-27
期刊：Immunity.
Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells
时间：2018-11-27
期刊：Nat Commun.
Single-cell transcriptional analysis reveals ILC-like cells in zebrafish
时间：2018-11-16
期刊：Sci Immunol.
Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages
时间：2018-11-12
期刊：Sci Immunol.
Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics
时间：2018-11-06
期刊：Cell Rep.
Human retinoic acid-regulated CD161+ regulatory T cells support wound repair in intestinal mucosa
时间：2018-11-05
期刊：Nat Immunol.
A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
时间：2018-11-01
期刊：cell
High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NK Cell Subsets in Humans and Mice
时间：2018-11-01
期刊：Immunity.
Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels
时间：2018-11-01
期刊：Nat Commun.
T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation
时间：2018-10-26
期刊：cell
FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells
时间：2018-10-25
期刊：Respir Res.
Gene expression variability across cells and species shapes innate immunity
时间：2018-10-24
期刊：nature
Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution
时间：2018-10-23
期刊：Cell Rep.
Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations
时间：2018-10-22
期刊：Nat Commun.
Joint single cell DNA-Seq and RNA-Seq of gastric cancer reveals subclonal signatures of genomic instability and gene expression
时间：2018-10-17
期刊：Biorxiv.
High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy
时间：2018-10-16
期刊：cell
The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
时间：2018-10-16
期刊：Immunity.
Over-expression of PD-1 does not predict leukemic relapse after allogeneic stem cell transplantation
时间：2018-10-04
期刊：Biol Blood -3-row Transplant.
RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses
时间：2018-10-04
期刊：cell
Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease
时间：2018-10-04
期刊：cell
Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency
时间：2018-10-02
期刊：Cell Rep.
Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease
时间：2018-10-01
期刊：Nat Med
Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA
时间：2018-09-24
期刊：Nat Commun.