研究课题：藏彝走廊地区人群遗传混合历史研究
合作单位：甘肃省证据科学技术研究与应用重点实验室、厦门大学人类学与民族学系、南洋理工大学、德国马普所、哈佛医学院等
出版刊物：American journal of physical anthropology（人类学领域的顶尖期刊《美国体质人类学学报》）
Abstract
Objectives: The Tibetan-Yi Corridor located on the eastern edge of Tibetan Plateau is suggested to be the key region for the origin and diversification of Tibeto-Burman speaking populations and the main route of the peopling of the Plateau. However, the genetic history of the populations in the Corridor is far from clear due to limited sampling in the northern part of the Corridor.
Materials and methods: We collected blood samples from 10 Tibetan and 10 Han Chinese individuals from Gansu province and genotyped about 600,000 genome-wide single nucleotide polymorphisms (SNPs).
Results: Our data revealed that the populations in the Corridor are all admixed on a genetic cline of deriving ancestry from Tibetans on the Plateau and surrounding lowland East Asians. The Tibetan and Han Chinese groups in the north of the Plateau show significant evidence of lowlevel West Eurasian admixture that could be probably traced back to 600900 years ago.
Discussion: We conclude that there have been huge population migrations from surrounding lowland onto the Tibetan Plateau via the Tibetan-Yi Corridor since the initial formation of Tibetans probably in Neolithic Time, which leads to the current genetic structure of Tibeto-Burman speaking populations.